EFFIPRO® Fipronil-Based Spot-On: One Solution, Dual Protection

Protect Pets from Fleas and Ticks and Perpetuating Flea Invasions

  • Dog
  • Cat

EFFIPRO® Spot-On Solution offers a unique protection to protect both the animal and its home from flea contamination . It outperforms fipronil + IGR flea and ticks spot-on thanks to the long lasting PPF effect, to prevent the emergence of flea eggs and larvae in the home up to 3 months (instead of 2). Ideal for indoor ecto protection.



EFFIPRO® Spot-On is a 10% w/v fipronil-based Spot-on solution (1ml of solution = 100mg of fipronil) which has the same qualitative and quantitative composition in terms of active substance (fipronil) as Frontline® Spot-on (Merial) with different excipients.

EFFIPRO® Spot-On contains fast-acting fipronil, which will kill fleas on your pet within within 24 hours and ticks within the 48 hours.



  1. EFFIPRO® Spot-On can be used for the treatment of flea (Ctenocephalides spp.) and tick (Dermacentor reticulatus) infestations in dogs and cats.
  2. Insecticidal efficacy against new infestations with adult fleas persists for up to 8 weeks in dogs
  3. The product has a persistent acaricidal efficacy against ticks (Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor reticulatus) for up to 4 weeks in dogs and up to 2 weeks in cats. 
  4. EFFIPRO® Spot-On can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis in dogs.



  1. Fipronil (activity on contact) + Pyriproxyfen (long-lasting Insect Growth Regulator - IGR)
  2. 1 month adulticides & 3 months of protection against re-infestation
  3. IGR; mimics  the chemical structure of juvenile hormone and inhibits its development (sterilize adult fleas) 
  4. Pyriproxyfen is resistant to sunlight and persistent on the pet skin even when shampooed (vs. 5-Methoprene) giving efficacy for up to 3 months
  5. Easy to give ISFM Award
  6. Spot-on/ Drop stop application


EFFIPRO® Spot-On is presented in thermoformed single-dose pipettes.

  • Fleas: Every 4 to 8 weeks in dogs, and every 4 weeks in cats
  • Ticks: Every 4 weeks in both dogs and cats



  • Kills fleas on pets within 24 hours, and ticks within 48 hours
  • Treats fleas for up to 5 weeks in cats and 8 weeks in dogs
  • Treats ticks for up to 2 weeks in cats and 4 weeks in dogs
  • Unique drop-lock pipette for easy administration
  • Approved for use in dogs > 2kg and over 8 weeks of age
  • Approved for use in cats > 1kg and over 8 weeks of age
  • Available in 5 presentations: Cats, Small Dogs, Medium Dogs, Large Dogs, Large Dogs, and Extra-Large Dogs
  • Fast-acting flea and tick treatment

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Complementary products

EFFIPRO® SPRAY 80ml: Fipronil 0.25% w/v Ecto Protection Spray for Dogs and Cats

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